- Uckfield - 43 companies
- Uddingston - 2 companies
- UK - 1 company
- Ulceby - 2 companies
- Ullapool - 1 company
- Ullesthorpe - 1 company
- Ulverston - 18 companies
- Umberleigh - 3 companies
- Uniformity Clothing Co - 1 company
- Upminster - 23 companies
- upon Tyne - 1 company
- Upper Beeding - 1 company
- Upper Belvedere - 1 company
- Upper Heyford - 1 company
- Upper Longdon - 1 company
- Upper Poppleton - 1 company
- Upper Sundon - 1 company
- Upper Wick Dursley - 1 company
- Upplands Väsby - 1 company
- Upton Upon Leves - 1 company
- Urmston - 1 company
- Usk - 6 companies
- Utah - 1 company
- Uttoxeter - 20 companies
- Uxbridge - 97 companies
